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Vitamin B12 treatments are considered safe for one very simple reason B vitamins are water-soluble, which means your body naturally filters out any excess vitamin through urination

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It requires a prescription from a licensed veterinarian

Repletion of vitamin B12 may improve response in patients resistant to antidepressants (10) , and in older adults with major depression, long-term supplementation with a combination of B12, B6, and folic acid enhanced antidepressant treatment efficacy (40)

Cloudiness, haziness, or any visible particles are clear signs of contamination